Current Clinical Trials | ECHO Associates

Current Trials

Genetic Risk Assessment

ECHO Open to Accrual Clinical Trials

Updated: 01/31/2025

Colorectal

Metastatic


WO42758 / INTRINSIC
A Phase I/Ib Global, Multicenter, Open-Label Umbrella Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients with Metastatic Colorectal Cancer (INTRINSIC)

Lung

HLX10-005-SCLC301-E (Astride)
A Randomized, Open-Label Study of HLX10 plus Chemotherapy (Carboplatin-
Etoposide) in comparison with Atezolizumab plus Chemotherapy in Previously
Untreated US Patients with Extensive Stage Small Cell Lung Cancer (ES-SCLC)
(Astride)

First Line Metastatic:

Amgen AMG 193 20230153
A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of AMG 193 in Subjects with Methylthioadenosine Phosphorylase (MTAP)-deleted Previously Treated Advanced Non-Small Cell Lung Cancer (NSCLC) 

Mirati 849-007
A Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced non-Small Cell Lung Cancer with KRAS G12C Mutation

OSE210C302 (Artemia)
A randomized, open-label, phase 3 trial comparing the efficacy and safety of OSE2101 versus docetaxel in HLA-A2 positive patients with metastatic Non-Small Cell Lung Cancer (NSCLC) and secondary resistance to immune checkpoint inhibitor (ICI)-Artemia study

Xencor XmAb717-06
 A Phase 1b/2, Open-label, Randomized Study of Vudalimab in Combination with Chemotherapy of Pembrolizumab in Combination with Chemotherapy as First-line Treatment in Patients with Advanced Non-small Cell lung Cancer

Prostate

D9723C00001
A Randomized, 2-cohort, Double-blind, Placebo-controlled, Phase III Study of
Saruparib (AZD5305) in Combination with Physician’s choice New Hormonal Agents
in Patients with HRRm and non-HRRm Metastatic Castration-Sensitive Prostate
Cancer (EvoPAR-Prostate01)

Solid Tumors

AMG 193 20230167
A Phase 1b Study Evaluating the safety, tolerability, Pharmacokinetics, and efficacy of AMG 193 alone or in combination with other therapies in subjects with Advanced Thoracic Tumors with Homozygous MTAP-deletion 
 
AMG 20230246
A Non-Interventional Biomarker Study on the molecular evaluation of Archival Tumor Tissue in subjects with advanced or metastatic malignancies

Supportive Care

LP-CT-PALO-202101
A randomized, Double-Blind, Double-dummy, Parallel Group Study to Assess the Efficacy and Safety of Palonosetron HCl Buccal Film versus IV Palonosetron 0.25 mg for the Prevention of Chemotherapy-induced Nausea and Vomiting in Cancer Patients Receiving Moderately Emetogenic Chemotherapy

OB202401 (Oxford Biodynamics)
A Prospective Real World Evidence Study (PROWES) for concordance rate of blood-
based 3D genome conformation mapping (Episwitch CiRT) to identify likelihood of
response and actual response rates to PD-(L)-1 checkpoint inhibitors across multiple
oncological indications
 
TP-CA-002 Tempus Gemini NSCLC Surveillance Study
A longitudinal multiomic biomarker profiling study of patients with Non-Small Cell Lung Cancer (NSCLC)
 
TP-CA-007 Tempus Aries
A Biobank Registry Platform Study in Oncology


For more information on clinical trials, please contact Dr. Susan Johnson, Director of Research sjohnson@echoct.com or 860-886-8362.  

To learn about phases of trials and what it means to participate, click here.